τουτο demonstrative pronoun - accusative singular neuter
touto  too'-to: that thing -- here (-unto), it, partly, self(-same), so, that (intent), the same, there(-fore, -unto), this, thus, where(-fore).
δε conjunction
de  deh: but, and, etc. -- also, and, but, moreover, now (often unexpressed in English).
γινωσκε verb - present active middle - second person singular
ginosko  ghin-oce'-ko: to know (absolutely) in a great variety of applications and with many implications (as follow, with others not thus clearly expressed)
οτι conjunction
hoti  hot'-ee: demonstrative, that (sometimes redundant); causative, because -- as concerning that, as though, because (that), for (that), how (that), (in) that, though, why.
εν preposition
en  en: in, at, (up-)on, by, etc.
εσχαταις adjective - dative plural feminine
eschatos  es'-khat-os: farthest, final (of place or time) -- ends of, last, latter end, lowest, uttermost.
ημεραις noun - dative plural feminine
hemera  hay-mer'-ah: age, + alway, (mid-)day (by day, (-ly), + for ever, judgment, (day) time, while, years.
ενστησονται verb - future middle deponent indicative - third person
enistemi  en-is'-tay-mee: to place on hand, i.e. (reflexively) impend, (participle) be instant -- come, be at hand, present.
καιροι noun - nominative plural masculine
kairos  kahee-ros': an occasion, i.e. set or proper time -- always, opportunity, (convenient, due) season, (due, short, while) time, a while.
χαλεποι adjective - nominative plural masculine
chalepos  khal-ep-os': difficult, i.e. dangerous, or (by implication) furious -- fierce, perilous.